v1.0 Now Available

An integrated ecosystem for
virome analysis

Seamlessly transition from raw metagenomic sequencing data to publication-ready ecological insights without writing a single line of code.

Launch Explorer App Read the Documentation

MetaViralyst Ecosystem Flowchart from Pipeline to Explorer

The MetaViralyst ecosystem enables seamless, reproducible virome analysis. Process raw sequencing reads through the robust Snakemake pipeline, and integrate the resulting matrices directly into the interactive Streamlit Explorer for real-time ecological insights.

Automated Discovery Pipeline

A robust Snakemake workflow taking raw reads through stringent quality control, de novo assembly, and dual-layer taxonomic verification.

Interactive Explorer

A code-free Streamlit app to explore composition, analyze diversity, and instantly perform differential abundance testing.

Rigorous Reproducibility

An entirely open-source approach built on robust Conda environments, Docker containers, and version-controlled public databases.

The Ecosystem Architecture

Two powerful components working seamlessly together to accelerate your research.

The Snakemake Pipeline

A robust, automated backend workflow for viral metagenomics. Handles quality control, host decontamination, de novo assembly, viral identification via geNomad, and high-resolution taxonomic annotation.

View Pipeline Repository

The Interactive Explorer

A code-free Streamlit frontend application. Ingests pipeline outputs to let you interactively explore taxonomic composition, calculate alpha/beta diversity, and perform differential abundance statistical testing.

View Explorer Repository

Documentation & Resources

Everything you need to get started and master the tools.

Pipeline Docs

Learn how to install, configure, and execute the Snakemake workflow across different environments.

Explorer Docs

Learn how to format inputs, navigate interactive modules, and interpret complex statistical outputs.

Reference DBs

Access pre-built, versioned reference databases and fully reproducible benchmark datasets.

Example Results

Download fully processed pipeline outputs, count matrices, and curated mock community results.

Cite MetaViralyst

The MetaViralyst manuscript is currently under review. If you use the pipeline or the Explorer application in your research, please cite our repository via Zenodo:

"MetaViralyst: An integrated ecosystem for reproducible end-to-end virome analysis and interactive exploration". Zenodo, DOI: [Zenodo DOI TBA]

An integrated ecosystem for virome analysis